en ميکروب شناسي Microbiology Research Article Research Article <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Times New Roman;"><span style="line-height:200%"><span style="unicode-bidi:embed"><span new="" roman="" times=""><b><span style="line-height:200%">Background</span></b><span style="line-height:200%">: Foodborne pathogens can significantly affect the public health and cause medical, social, and economic burden. <em>Listeria monocytogenes</em>, <em>Salmonella </em><i>&shy;enterica<em>, and </em><span style="background:white"><span style="color:black">Yersinia</span></span> enterocolitica </i>are important foodborne pathogens that can cause various diseases. Plant-derived compounds are promising bioactive substances with inhibitory effects against bacteria. <i>Perovskia abrotanoides </i>Kar. is a medical plant with broad therapeutic activities. In the present study, we aimed to investigate the inhibitory effects of <i>P. abrotanoides </i>extracts against some foodborne pathogens.</span></span></span></span><br> <span style="line-height:200%"><span style="unicode-bidi:embed"><span new="" roman="" times=""><b><span style="line-height:200%">Methods:</span></b><span style="line-height:200%"> Flowering branches of<i> P. abrotanoides </i>were collected in 2018 and 2019 from three different habitats in the eastern Alborz Mountains, Iran. The antimicrobial activity of the extracts was evaluated using the agar well diffusion test. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extracts were determined against <em>L. monocytogenes</em>, <em>S. </em><i>&shy;enterica<em>, and </em><span style="background:white"><span style="color:black">Y. </span></span>enterocolitica</i>. In addition, the antioxidant activity of the extracts was investigated by the DPPH test. </span></span></span></span><br> <span style="line-height:200%"><span style="unicode-bidi:embed"><span new="" roman="" times=""><b><span style="line-height:200%">Results:</span></b><span style="line-height:200%"> The lowest MIC (200 &micro;g/ml) and MBC (400 &micro;g/ml) values against <i>Y. enterocolitica </i>were related to the ethyl acetate extract of plants collected from habitat 1 in 2019. The lowest MIC (50 &micro;g/ml) and MBC (400 &micro;g/ml) values against <i>L.&shy;&shy; monocytogenes</i> were related to the dichloromethane extract of plants collected from habitat 1 in 2019. All extracts showed antioxidant properties. Results of one-way ANOVA indicated that the DPPH scavenging activity of extracts from plants collected in 2019 was greater than that of those collected in 2018. In most cases, the methanol and ethyl acetate extracts showed more radical scavenging potential.</span></span></span></span><br> <span style="line-height:200%"><span style="unicode-bidi:embed"><span new="" roman="" times=""><b><span style="line-height:200%">Conclusion:</span></b><span style="line-height:200%"> It seems that <i>P. abrotanoides </i>is a rich source of antimicrobial and antioxidant compounds with great potential for use in the pharmaceutical and food industries. </span></span></span></span></span></span></div> Listeria monocytogenes,Yersinia enterocolitica,Salmonella enterica,Antioxidant, 45 54 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1019-1&slc_lang=en&sid=1 Farzane Maryam m.farzane.208@gmail.com 100319475328460032009 100319475328460032009 No Department of Plant sciences, School of Biology, Damghan University, Damghan, Iran Poozesh Vahid poozesh@du.ac.ir 100319475328460032010 100319475328460032010 Yes Department of Plant sciences, School of Biology, Damghan University, Damghan, Iran Atefe Amirahmadi a.amirahmadi@du.ac.ir 100319475328460032011 100319475328460032011 No Department of Plant sciences, School of Biology, Damghan University, Damghan, Iran Fatemeh Salimi f.salimi@du.ac.ir 100319475328460032012 100319475328460032012 No Department of Molecular & Cellular, School of Biology, Damghan University, Damghan, Iran