fa سرو اپیدمیولوژی هرپس سیمپلکس تیپ 1 در مراجعین به آزمایشگاههای شهر گرگان سال 1385 Abstract Backgrounds and objectives: Herpes simplex virus type 1 (HSV- 1) infections are mostly shown as a Herpes disease, but It causes conjunctivitis, genital herpes, encephalitis and newborn herpes. This study was conducted to determine the sero-epidemiologic prevalence of herpes simplex virus type 1 in cases referred to clinical laboratories of Gorgan, Iran. Material and methods: In this cross sectional study, we did random blood sampling on 406 cases referred to the Gorgan city's clinical laboratories. These samples were analyzed for HSV-1 Immunoglobulin G and M antibodies using type- specific enzymelinked Immunoassays (ELISA). Results: Of 406 participants, the HSV-1 seroprevalence is 49% (44.3% and 4.7% for IgG and IgM respectively). There is not significant relationship between seropositive HSV-1 and gender, ethnicity, age and marital status. Conclusion: Sero-epidemiological of HSV-1 in Gorgan is the same of the other places in Iran, but it is higher than European and lower than African countries. It seems that the people’s culture is very important. Therefore it needs to be investigated more. Keywords: HSV-1, Antibody, Gorgan. Keywords: HSV-1, Antibody, Gorgan. 0 0 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-46&slc_lang=fa&sid=1 M Hedayat Mofidi سید محمد هدایت مفیدی mofidi_h@yahoo.com 100319475328460013107 100319475328460013107 Yes Instructor of Immunology Golestan دانشگاه علوم پزشکی گلستان A Moradi عبدالوهاب مرادی 100319475328460013108 100319475328460013108 No دانشگاه علوم پزشکی گلستان M Saeedi محسن سعیدی 100319475328460013109 100319475328460013109 No دانشگاه علوم پزشکی گلستان N Behnampoor ناصر بهنام پور 100319475328460013110 100319475328460013110 No دانشکده پزشکی،دانشگاه علوم پزشکی گلستان J Arab YaraMohammadi جواد عرب یار محمدی 100319475328460013111 100319475328460013111 No دانشکده پزشکی،دانشگاه علوم پزشکی گلستان