fa تحقيقي Original Paper <div><strong>ABSTRACT</strong><br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Background and Objectives:</strong> The unfavorable lipid profile in obese individuals is associated with high incidence of various diseases including cardiovascular disease, hypertension, etc. Dieting for weight loss and physical activity are among the most important factors affecting the serum lipid profile. The aim of this study was to compare the effect of diet with and without physical activity on body mass index and serum lipid profile of obese women.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Methods:</strong> This clinical trial was performed in 2011 on 39 obese women referred to a weight loss and nutrition counseling center. Subjects were randomly divided into an active group (diet and exercise) and inactive group (diet without exercise). Blood sampling was done before the intervention and two months after the intervention. Data was analyzed using SPSS-16 and t-test.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Results:</strong> Mean level of triglyceride reduced significantly in both groups. Mean level of cholesterol and low-density lipoprotein decreased significantly only in the active group. The Mean level of high-density lipoprotein in the two groups had no significant difference.<br> Conclusion: The results indicate that dieting for weight loss along with short-term physical activity improves serum levels of cholesterol and low-density lipoprotein, but does not affect serum HDL level.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Keywords:</strong> Diet, Exercise, Triglyceride, Cholesterol, LDL, HDL.</div> Diet, Exercise, Triglyceride, Cholesterol, LDL, HDL. 7 11 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-441&slc_lang=fa&sid=1 Mohadese Namjoo 100319475328460012475 100319475328460012475 No Laboratory Sciences Research Center, Department of Laboratory Sciences, School of Paramedical Sciences, Golestan University of Medical Sciences, Gorgan, Iran Ali Taheri 100319475328460012476 100319475328460012476 No Faculty of Advanced Medical Technologies, Golestan Univercity of Medical Sciences, Gorgan, Iran Maryam Moradi 100319475328460012477 100319475328460012477 No Department of Biochemistry, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran Mojgan Nejabat 100319475328460012478 100319475328460012478 No Department of Chemistry, Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran Zahra Gari 100319475328460012479 100319475328460012479 No Department of Medical Virology, School of Medicine, Golestan Univercity of Medical Sciences, Gorgan, Iran Maryam Saboktakinrizi maryamsaboktakin@yahoo.com 100319475328460012480 100319475328460012480 Yes Department of Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran