Showing 4 results for Lipid Profile
Dinarvand, Gh, Veis Raygani, A, Ghanbari, N,
Volume 9, Issue 1 (4-2015)
Abstract
Abstract
Background and Objective: T3 resin uptake test indicates the availability of thyroxin binding globulin (TBG), which is the carrier of a large amount of T3 and T4 in blood. We aimed to study the relationship between serum T3 Resin Uptake and serum lipids profile.
Material and Methods: The participants aged 14.80 ± 38.29 were both males (59 29.5%) and females (141 70.5 %). T3 Resin Uptake was measured by Immunoassay method and serum lipid profile components (cholesterol, triglycerides, HDL-C, LDL-C, and VLDL) were measured by the kit.
Results: Significant negative correlation was observed between serum T3 Resin Uptake and cholesterol, triglycerides and LDL-C (P≤ 0.05), but that was not the case for HDL-C and VLDL.
Conclusion: Serum T3 Resin Uptake can be evaluated to assess the risk factors related to cardiovascular disorders.
Keywords: Cholesterol, Triglycerides, T3 Resin Uptake, lipoprotein, Lipid Profile
Mahtab Moazzami , Asra Askari ,
Volume 12, Issue 2 (3-2018)
Abstract
ABSTRACT
Background and objectives: The aim of this study was to investigate the effects of six months of aerobic exercise on lipid profile, inflammatory markers, and risk factors of cardiovascular disease in middle-aged obese women.
Methods: Fifteen obese woman (age range: 35 to 45 years) with BMI of ≥30 Kg/m2 were enrolled via purposeful and convenience sampling. The participants were randomly divided into training (n=10) and control (n=5) groups. Blood samples (7 ml) were taken from all participants before the first training session and after the last training session. The women performed 60 minutes of aerobic exercise at 55-65% of heart rate reserve, three sessions a week, for six months. Data was analyzed using independent and paired t-tests and Mann-Whitney U and Wilcoxon tests at significance of 0.05.
Results: After the six-month aerobic exercise, C-reactive protein, low-density lipoprotein, triglycerides, total cholesterol and high-density lipoprotein/total cholesterol decreased significantly. The exercise intervention also caused a significant increase in the concentrations of high-density lipoprotein and apolipoprotein A.
Conclusion: Aerobic exercise can reduce the level of inflammatory markers associated with risk of cardiovascular disease and atherosclerosis.
Keywords: Lipid profile, Inflammatory markers, Obese women, Apolipoprotein, Aerobic exercise.
Mojtaba Abbasi, Amirhooman Asadi, Hadis Musavi,
Volume 13, Issue 6 (11-2019)
Abstract
Background and Objectives: Reduced insulin secretion in Type II Diabetes Mellitus (T2DM) results in fat accumulation in hepatocytes and increase in liver enzymes. The hepatocyte destruction due to non-alcoholic fatty liver is associated with increased risk of cardiovascular diseases. Therefore, the aim of this study is to evaluate the association of liver transaminases with lipid profile in T2DM patients compared to healthy subjects.
Methods: A total of 1000 subjects (500 males and females with T2DM and 500 healthy subjects) participated in this case-control study. Diagnosis of T2DM was made based on the World Health Organization (WHO) criteria. Fasting blood samples (5 ml) were obtained from all subjects in the morning and the serum was extracted for the assessment of biochemical parameters was used to compare parameters between healthy and T2DM patients. Data were analyzed by SPSS version 20 and using Mann-Whitney test and Spearman correlation coefficient.
Results: The serum total cholesterol (TCH), triglyceride, Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), TCH/high density lipoprotein (HDL-C) ratio and atherogenecity index plasma were significantly higher in T2DM group compared to healthy individuals (p≤0.006). Among the lipid profile parameters only Risk ratio (TCH/HDL-C) was positively correlated with ALT (p=0.037) while no significant correlation was observed for other variables (P>0.05)
Conclusion: T2DM Patients have higher lipid profile, atherogenecity index and liver enzymes compared to healthy individuals. Furthermore, TCH/HDL-C was significantly correlated with ALT.
Mahrooyeh Haji-Abolhasan Varaminfard, Mina Ebrahimi-Rad, Seifoddin Javadian, Mahmood Beheshti Monfared, Seyedeh Fatemeh Sadati Khalili, Reza Saghiri,
Volume 20, Issue 2 (6-2026)
Abstract
Background: Although several clinical and laboratory diagnostic approaches have been developed for Coronary Artery Disease (CAD), rates of mortality and morbidity have remained high, which may be due to defective diagnostic markers. Here, we evaluated the serum levels of selected trace elements (Zn, Se, and Cu) in CAD patients and healthy subjects and assessed their diagnostic values in CAD.
Methods: 53 cardiologist-approved CAD patients and 48 age and sex-matched healthy controls were recruited. The serum levels of Zn, Se, and Cu, were assessed using the atomic absorption method. GraphPad v.8.4 and SPSS v.18 software were used for statistical analyses.
Results: The serum levels of Zn and Se were significantly lower in the CAD patients than in controls (P = 0.0008 and P < 0.0001, respectively). In contrast, CAD patients showed significantly higher levels of Cu (P = 0.0064). Concerning the ROC curve analyses, the area under the curve (AUC) for Zn was 0.6563 (P = 0.0069). Setting the cut-off value at 1.255 μg/mL gave a sensitivity of 56.60%, specificity of 66.67%, and likelihood ratio (LR) of 1.698. AUC for Se was 0.8595 (P<0.0001). The optimum cut-off value at 86.50 ng/ml level gave a sensitivity of 83.02%, specificity of 75.00%, and LR of 3.321. The AUC for Cu was 0.6557 (P = 0.0071). The optimum cut-off value at 1.225 μg/mL level gave a sensitivity of 62.26%, specificity of 64.58%, and LR of 1.758.
Conclusion: Our study showed that selenium can be a biomarker with reliable diagnostic value for CAD.
goums.ac.ir
yahoo.com